| 586 | 192 | 148 |
| 下载次数 | 被引频次 | 阅读次数 |
本实验室在异黄酮植物雌激素-大豆黄酮对大鼠、肉用仔鸡、仔猪和反刍动物生长及有关激素水平的影响方面进行了系列研究。结果表明:具有弱的雌激素样活性的大豆黄酮可显著增加雄性动物和公鸡的增重及饲料利用效率,提高血液睾酮、β-内啡肽、生长激素、胰岛素样生长因子一Ⅰ、三碘甲腺原氨酸、甲状腺素和胰岛素水平,但却使血液脲氮和胆固醇浓度降低,从而促进肌肉蛋白质沉积,加速肌肉生长和发育。然而,大豆黄酮对雌性动物生长和代谢激素状态无显著影响。并讨论了有关调控雄性动物肌肉生长的神经内分泌机制。
Abstract:A series of experiments investigating the effects of daidzein——one of isoflavonic phytoestrogen on the growth and involved hormones of rats,broiler chickens,piglets and ruminants were conducted in our laboratory.The results showed that daidzein,exhibiting weak estrogen like activity,increased body weight gain and feed efficiency,elevated the blood levels of testosterone,β endorphin,growth hormone,IGF 1,T3,T4 and insulin in male animals and birds significantly,but decreased the blood urea nitrogen and cholesterol concentrations,subsequently stimulating protein accretion in the muscle and accelerating the muscle growth and development.However,no change of growth and metabolic hormone status in female was observed.The mechanism of neuroendocrine regulation involved in the muscle growth of male animals has been discussed.
1韩正康.黄酮化合物调控畜禽神经内分泌及生产性能的研究,畜禽优质高产生物调控研讨会论文摘要汇编.中国畜牧兽医学会动物生理生化学会.1994,1~32王国杰,韩正康.红三叶草总异黄酮对小公鸡生长及血液睾酮水平的影响,动物学研究,1994,15(3):65~693王国杰,韩正康,陈伟华.大豆黄酮对大鼠肌肉生长和几种内源激素水平的影响.动物学研究,1995,16(1):23~294刘根桃,陈伟华,陈杰,韩正康,大豆黄酮对断奶仔鼠的作用研究,动物生理生化第五次学术会议论文摘要汇编.中国畜牧兽医学会动物生理生化学会.1997,835王国杰,韩正康,陈杰等.大豆黄酮对肉鸡生长的影响及其作用机制研究.广东畜牧兽医科技,1994,19(3):4~66HanZhengkang,WangGuojie,Studiesofphytoestrogen(daidzein)afectingthegrowthandsexhormonelevelsinbroilerⅦWorldCon-ferenceonAnimalProduction.Edmondon,Canada,1993,152~1537赵志辉,徐银学,陈伟华等.大豆黄酮对仔猪血液中与生长有关的激素和代谢物的影响.动物生理生化第五次学术会议论文摘要汇编,中国畜牧兽医学会动物生理生化学会.1997,838LiuGentao,ChenJie,ChenWeihuaetal.Genderdiferenceoffed-ingisoflavonicphytoestrogensonlatepregnantsowsonthegrowthinnursingpigletsandendocrinefunctioninvolved.The8thAAAPAnimalScineceCongress,Japan,Proceedings.1996,(2):750~7519杨国宇,陈杰,陈伟华等.IFV-D对反刍动物内源性睾酮水平及瘤胃消化代谢的影响.畜禽优质高产生物调控研讨会论文摘要汇编,中国畜牧兽医学会动物生理生化学会,1994,2910王国杰,韩正康,克伦特罗和异黄酮植物雌激素对骨骼肌细胞生长的影响.南京农业大学学报,1993,16(增刊):15-18
基本信息:
引用信息:
[1]韩正康.异黄酮植物雌激素——大豆黄酮对雄性动物生长及其有关内分泌的研究[J].畜牧与兽医,1999(01).
基金信息:
国家教委博士点基金,国家自然科学基金